Development of a NS2B/NS3 protease inhibition assay using AlphaScreen® beads for screening of anti-dengue activities

Background: Dengue infection is an endemic infectious disease and it can lead to dengue fever, dengue hemorrhagic fever, and/or dengue shock syndromes. Dengue NS2B/NS3 protease complex is essential for viral replication and is a primary target for anti-dengue drug development. In this study, a NS2B/...

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Bibliographic Details
Main Authors: Abduraman, Muhammad Asyraf, Hariono, Maywan, Yusof, Rohana, Abd Rahman, Noorsaadah, Wahab, Habibah A., Tan, Mei Lan
Format: Article
Published: Elsevier 2018
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Online Access:http://eprints.um.edu.my/22731/
https://doi.org/10.1016/j.heliyon.2018.e01023
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