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Thioguanine-based DENV-2 NS2B/NS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling

Dengue virus Type 2 (DENV-2) is predominant serotype causing major dengue epidemics. There are a number of studies carried out to find its effective antiviral, however to date, there is still no molecule either from peptide or small molecules released as a drug. The present study aims to identify sm...

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Bibliographic Details
Main Authors: Hariono, Maywan, Choi, Sy Bing, Roslim, Ros Fatihah, Mohd. Nawi, Mohamed Sufian, Tan, Mei Lan, Kamarulzaman, Ezatul Ezleen, Mohamed, Nornisah, Yusof, Rohana, Othman, Shatrah, Abd Rahman, Noorsaadah, Othman, Rozana, A. Wahab, Habibah
Format: Article
Language:English
English
English
Published: Public Library of Science 2019
Subjects:
RS Pharmacy and materia medica
RS403 Materia Medica-Pharmaceutical Chemistry
Online Access:http://irep.iium.edu.my/47962/1/47962_Thioguanine-based%20DENV-2%20NS2B-NS3.pdf
http://irep.iium.edu.my/47962/2/47962_Thioguanine-based%20DENV-2%20NS2B-NS3_SCOPUS.pdf
http://irep.iium.edu.my/47962/3/47962_Thioguanine-based%20DENV-2%20NS2B-NS3_WOS.pdf
http://irep.iium.edu.my/47962/
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210869&type=printable
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Internet

http://irep.iium.edu.my/47962/1/47962_Thioguanine-based%20DENV-2%20NS2B-NS3.pdf
http://irep.iium.edu.my/47962/2/47962_Thioguanine-based%20DENV-2%20NS2B-NS3_SCOPUS.pdf
http://irep.iium.edu.my/47962/3/47962_Thioguanine-based%20DENV-2%20NS2B-NS3_WOS.pdf
http://irep.iium.edu.my/47962/
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210869&type=printable

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