T-Cell Exhaustion in Chronic Infections: Reversing the State of Exhaustion and Reinvigorating Optimal Protective Immune Responses
T-cell exhaustion is a phenomenon of dysfunction or physical elimination of antigen-specific T cells reported in human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) infections as well as cancer. Exhaustion appears to be often restricted to CD8+ T cells responses...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Published: |
Frontiers Media
2018
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/20831/ https://doi.org/10.3389/fimmu.2018.02569 |
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