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A new oxathiolane fromEnterobacter cloacae

Enterobacter cloacae is a versatile bacterial species inhabiting a wide variety of niches and is capable of metabolising a wide variety of substances as energy resources. The fermentation culture of this bacterial species has successfully yielded one new compound, Rimboxa (1) and three known compoun...

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Main Authors: Yap, A.C., Teoh, W.Y., Chan, Kok Gan, Sim, Kae Shin, Choo, Yeun Mun
Format: Article
Published: Taylor & Francis 2015
Subjects:
Q Science (General)
QD Chemistry
QH Natural history
Online Access:http://eprints.um.edu.my/19406/
http://dx.doi.org/10.1080/14786419.2014.983507
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spelling my.um.eprints.194062019-12-23T02:27:36Z http://eprints.um.edu.my/19406/ A new oxathiolane fromEnterobacter cloacae Yap, A.C. Teoh, W.Y. Chan, Kok Gan Sim, Kae Shin Choo, Yeun Mun Q Science (General) QD Chemistry QH Natural history Enterobacter cloacae is a versatile bacterial species inhabiting a wide variety of niches and is capable of metabolising a wide variety of substances as energy resources. The fermentation culture of this bacterial species has successfully yielded one new compound, Rimboxa (1) and three known compounds, i.e. indole-3-carboxaldehyde (2), indole-3-acetic acid (3) and 3,4-di-t-butylaniline (4). Rimboxa (1) is shown to possess the 1,2-oxathiolane core structure. 3,4-Di-t-butylaniline (4) is isolated for the first time from a natural resource. These compounds were isolated and characterised using extensive chromatographic and spectroscopic methods, and were subjected to cytotoxicity evaluations. Taylor & Francis 2015 Article PeerReviewed Yap, A.C. and Teoh, W.Y. and Chan, Kok Gan and Sim, Kae Shin and Choo, Yeun Mun (2015) A new oxathiolane fromEnterobacter cloacae. Natural Product Research, 29 (8). pp. 722-726. ISSN 1478-6419 http://dx.doi.org/10.1080/14786419.2014.983507 doi:10.1080/14786419.2014.983507
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
QD Chemistry
QH Natural history
spellingShingle Q Science (General)
QD Chemistry
QH Natural history
Yap, A.C.
Teoh, W.Y.
Chan, Kok Gan
Sim, Kae Shin
Choo, Yeun Mun
A new oxathiolane fromEnterobacter cloacae
description Enterobacter cloacae is a versatile bacterial species inhabiting a wide variety of niches and is capable of metabolising a wide variety of substances as energy resources. The fermentation culture of this bacterial species has successfully yielded one new compound, Rimboxa (1) and three known compounds, i.e. indole-3-carboxaldehyde (2), indole-3-acetic acid (3) and 3,4-di-t-butylaniline (4). Rimboxa (1) is shown to possess the 1,2-oxathiolane core structure. 3,4-Di-t-butylaniline (4) is isolated for the first time from a natural resource. These compounds were isolated and characterised using extensive chromatographic and spectroscopic methods, and were subjected to cytotoxicity evaluations.
format Article
author Yap, A.C.
Teoh, W.Y.
Chan, Kok Gan
Sim, Kae Shin
Choo, Yeun Mun
author_facet Yap, A.C.
Teoh, W.Y.
Chan, Kok Gan
Sim, Kae Shin
Choo, Yeun Mun
author_sort Yap, A.C.
title A new oxathiolane fromEnterobacter cloacae
title_short A new oxathiolane fromEnterobacter cloacae
title_full A new oxathiolane fromEnterobacter cloacae
title_fullStr A new oxathiolane fromEnterobacter cloacae
title_full_unstemmed A new oxathiolane fromEnterobacter cloacae
title_sort new oxathiolane fromenterobacter cloacae
publisher Taylor & Francis
publishDate 2015
url http://eprints.um.edu.my/19406/
http://dx.doi.org/10.1080/14786419.2014.983507
_version_ 1654960690727747584
score 13.211869

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