A new oxathiolane fromEnterobacter cloacae

Enterobacter cloacae is a versatile bacterial species inhabiting a wide variety of niches and is capable of metabolising a wide variety of substances as energy resources. The fermentation culture of this bacterial species has successfully yielded one new compound, Rimboxa (1) and three known compoun...

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Bibliographic Details
Main Authors: Yap, A.C., Teoh, W.Y., Chan, Kok Gan, Sim, Kae Shin, Choo, Yeun Mun
Format: Article
Published: Taylor & Francis 2015
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Online Access:http://eprints.um.edu.my/19406/
http://dx.doi.org/10.1080/14786419.2014.983507
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Summary:Enterobacter cloacae is a versatile bacterial species inhabiting a wide variety of niches and is capable of metabolising a wide variety of substances as energy resources. The fermentation culture of this bacterial species has successfully yielded one new compound, Rimboxa (1) and three known compounds, i.e. indole-3-carboxaldehyde (2), indole-3-acetic acid (3) and 3,4-di-t-butylaniline (4). Rimboxa (1) is shown to possess the 1,2-oxathiolane core structure. 3,4-Di-t-butylaniline (4) is isolated for the first time from a natural resource. These compounds were isolated and characterised using extensive chromatographic and spectroscopic methods, and were subjected to cytotoxicity evaluations.