Synthesis of Apoptotic New Quinazolinone-Based Compound and Identification of its Underlying Mitochondrial Signalling Pathway in Breast Cancer Cells

The anti-carcinogenic effect of the new quinazolinone compound, named MMD, was tested on MCF-7 human breast cancer cell line. The synthesis of quinazolinone-based compounds attracted strong attention over the past few decades as an alternative mean to produce analogues of natural products. Quinazoli...

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Bibliographic Details
Main Authors: Zahedifard, M., Faraj, F.L., Paydar, M., Looi, C.Y., Hasandarvish, P., Hajrezaie, M., Kamalidehghan, B., Majid, N.A., Khalifa, S.A.M., Ali, H.M., Abdulla, M.A., El-Seedi, H.R.
Format: Article
Published: Bentham Science Publishers 2015
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Online Access:http://eprints.um.edu.my/19314/
http://dx.doi.org/10.2174/1381612821666150326104952
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