Synthesis of Apoptotic New Quinazolinone-Based Compound and Identification of its Underlying Mitochondrial Signalling Pathway in Breast Cancer Cells
The anti-carcinogenic effect of the new quinazolinone compound, named MMD, was tested on MCF-7 human breast cancer cell line. The synthesis of quinazolinone-based compounds attracted strong attention over the past few decades as an alternative mean to produce analogues of natural products. Quinazoli...
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Main Authors: | Zahedifard, M., Faraj, F.L., Paydar, M., Looi, C.Y., Hasandarvish, P., Hajrezaie, M., Kamalidehghan, B., Majid, N.A., Khalifa, S.A.M., Ali, H.M., Abdulla, M.A., El-Seedi, H.R. |
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Format: | Article |
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Bentham Science Publishers
2015
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Online Access: | http://eprints.um.edu.my/19314/ http://dx.doi.org/10.2174/1381612821666150326104952 |
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