Transcriptome profiling of monocytes from XLA patients revealed the innate immune function dysregulation due to the BTK gene expression deficiency
X-linked agammaglobulinemia (XLA) is a rare genetic disorder, caused by mutations in BTK (Bruton's Tyrosine Kinase) gene. Deep high-throughput RNA sequencing (RNA-Seq) approach was utilized to explore the possible differences in transcriptome profiles of primary monocytes in XLA patients compar...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2017
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/18995/1/Transcriptome_profiling_of_monocytes_from_XLA_patients_revealed_the_innate_immune_function_dysregulation_due_to_the_BTK_gene_expression_deficiency.pdf http://eprints.um.edu.my/18995/ http://dx.doi.org/10.1038/s41598-017-06342-5 |
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