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Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail

The significance of this research is to design, synthesis and determination of biological activities of resveratrol (stilbene) analogue attached to Zn2+-cyclen complex. Three established reactions had been used in order to accomplish the research. First, the 3,5- dimethoxybenzaldehyde was utilizes a...

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Main Author: Mohd Ismail, Nafiza
Format: Thesis
Language:English
Published: 2005
Subjects:
QD Chemistry
RM Therapeutics. Pharmacology
Online Access:https://ir.uitm.edu.my/id/eprint/98655/1/98655.PDF
https://ir.uitm.edu.my/id/eprint/98655/
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spelling my.uitm.ir.986552024-07-22T04:32:55Z https://ir.uitm.edu.my/id/eprint/98655/ Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail Mohd Ismail, Nafiza QD Chemistry RM Therapeutics. Pharmacology The significance of this research is to design, synthesis and determination of biological activities of resveratrol (stilbene) analogue attached to Zn2+-cyclen complex. Three established reactions had been used in order to accomplish the research. First, the 3,5- dimethoxybenzaldehyde was utilizes as a starting material of the Wittig reaction. Subsequently, protection of the 4-iodophenol using TBDMS-C1 to yield 4-iodo-tert- butyldimethylsilylphenylether. Product of the Wittig reaction and 4-iodo-/er/- butyldimethylsilylphenylether were then use to synthesize the stilbene analogue. The synthesized compounds were then, purified by chromatographic techniques and sent for 'H-NMR and UV characterization. The outcomes of this research did not make the grade, and the research was postponed due time constraint. 2005 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/98655/1/98655.PDF Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail. (2005) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam).
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic QD Chemistry
RM Therapeutics. Pharmacology
spellingShingle QD Chemistry
RM Therapeutics. Pharmacology
Mohd Ismail, Nafiza
Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
description The significance of this research is to design, synthesis and determination of biological activities of resveratrol (stilbene) analogue attached to Zn2+-cyclen complex. Three established reactions had been used in order to accomplish the research. First, the 3,5- dimethoxybenzaldehyde was utilizes as a starting material of the Wittig reaction. Subsequently, protection of the 4-iodophenol using TBDMS-C1 to yield 4-iodo-tert- butyldimethylsilylphenylether. Product of the Wittig reaction and 4-iodo-/er/- butyldimethylsilylphenylether were then use to synthesize the stilbene analogue. The synthesized compounds were then, purified by chromatographic techniques and sent for 'H-NMR and UV characterization. The outcomes of this research did not make the grade, and the research was postponed due time constraint.
format Thesis
author Mohd Ismail, Nafiza
author_facet Mohd Ismail, Nafiza
author_sort Mohd Ismail, Nafiza
title Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_short Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_full Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_fullStr Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_full_unstemmed Design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / Nafiza Mohd Ismail
title_sort design, synthesis and determination of biological activities of stilbene analogue attached to zinc (ii)-cyclen complex / nafiza mohd ismail
publishDate 2005
url https://ir.uitm.edu.my/id/eprint/98655/1/98655.PDF
https://ir.uitm.edu.my/id/eprint/98655/
_version_ 1806422116339286016
score 13.211869

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