Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa
The synthesis of 4-allyoxy-11, 13-dimethoxystilbene has been made using a series of reactions. Protected iodophenol reaction was the first step using allyl bromide as a protecting agent. After that, through Wittig reaction the protected styrene was successfully synthesized. Both compound finally wer...
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2005
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my.uitm.ir.984852024-08-27T18:11:44Z https://ir.uitm.edu.my/id/eprint/98485/ Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa Che Pa, Mohd Farizh QD Chemistry RM Therapeutics. Pharmacology The synthesis of 4-allyoxy-11, 13-dimethoxystilbene has been made using a series of reactions. Protected iodophenol reaction was the first step using allyl bromide as a protecting agent. After that, through Wittig reaction the protected styrene was successfully synthesized. Both compound finally were coupled in the presence of palladium chloride as a catalyst and triphenylphospine as a ligand via Heck reaction to give about 28.84% yield. TLC, UV spectrophotometer and NMR spectrometer were used in the determination of every product for every step. However, the desired compound, which is expected to be formed, was not successfully synthesized due to unknown reason. 2005 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/98485/1/98485.PDF Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa. (2005) Degree thesis, thesis, Universiti Teknologi MARA (Kampus Puncak Alam). |
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QD Chemistry RM Therapeutics. Pharmacology Che Pa, Mohd Farizh Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa |
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The synthesis of 4-allyoxy-11, 13-dimethoxystilbene has been made using a series of reactions. Protected iodophenol reaction was the first step using allyl bromide as a protecting agent. After that, through Wittig reaction the protected styrene was successfully synthesized. Both compound finally were coupled in the presence of palladium chloride as a catalyst and triphenylphospine as a ligand via Heck reaction to give about 28.84% yield. TLC, UV spectrophotometer and NMR spectrometer were used in the determination of every product for every step. However, the desired compound, which is expected to be formed, was not successfully synthesized due to unknown reason. |
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Thesis |
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Che Pa, Mohd Farizh |
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Che Pa, Mohd Farizh |
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Che Pa, Mohd Farizh |
title |
Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa |
title_short |
Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa |
title_full |
Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa |
title_fullStr |
Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa |
title_full_unstemmed |
Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa |
title_sort |
synthesis of 4-allyloxy-11, 13-dimethoxystilbene / mohd farizh che pa |
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2005 |
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https://ir.uitm.edu.my/id/eprint/98485/1/98485.PDF https://ir.uitm.edu.my/id/eprint/98485/ |
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13.223943 |