Synthesis of 4-allyloxy-11, 13-dimethoxystilbene / Mohd Farizh Che Pa
The synthesis of 4-allyoxy-11, 13-dimethoxystilbene has been made using a series of reactions. Protected iodophenol reaction was the first step using allyl bromide as a protecting agent. After that, through Wittig reaction the protected styrene was successfully synthesized. Both compound finally wer...
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| Format: | Thesis |
| Language: | English |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/98485/1/98485.PDF https://ir.uitm.edu.my/id/eprint/98485/ |
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| Summary: | The synthesis of 4-allyoxy-11, 13-dimethoxystilbene has been made using a series of reactions. Protected iodophenol reaction was the first step using allyl bromide as a protecting agent. After that, through Wittig reaction the protected styrene was successfully synthesized. Both compound finally were coupled in the presence of palladium chloride as a catalyst and triphenylphospine as a ligand via Heck reaction to give about 28.84% yield. TLC, UV spectrophotometer and NMR spectrometer were used in the determination of every product for every step. However, the desired compound, which is expected to be formed, was not successfully synthesized due to unknown reason. |
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