Lyophilized amorphous dispersion of telmisartan in a combined carrier–alkalizer system: formulation development and in vivo study
Telmisartan suffers from low oral bioavailability due to its poor water solubility. The research work presents a formulation of solid dispersed (SD) telmisartan formulation as a ternary mixture of a drug, a polymeric carrier (poly(vinylpyrrolidone) (PVP) K30), and an alkalizer (Na2CO3). The preparat...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
American Chemical Society
2020
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/88239/7/88239_Lyophilized%20amorphous%20dispersion.pdf http://irep.iium.edu.my/88239/8/88239_Lyophilized%20amorphous%20dispersion%20of%20telmisartan%20in%20a%20combined%20_Scopus.pdf http://irep.iium.edu.my/88239/ https://pubs.acs.org/doi/10.1021/acsomega.0c04588 |
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