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Microencapsulation of fish oil using supercritical antisolvent process

In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. Th...

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Main Authors:	Karim, Fahim Tamzeedul, Gahfoor, Kashif, Ferdosh, Sahena, Al-Juhaimi, Fahad, Ali, Eaqub, Yunus, Kamaruzzaman, Hamed, Mir Hoseini, Islam, Ashraful, Asif, Mohammad, Sarker, Md. Zaidul Islam
Format:	Article
Language:	English English English
Published:	Elsevier Taiwan LLC 2017
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/58010/1/Microencapsulation%20of%20fish%20oil%20using%20supercritical.pdf http://irep.iium.edu.my/58010/7/58010_Microencapsulation%20of%20fish%20oil_WOS.pdf http://irep.iium.edu.my/58010/8/58010_Microencapsulation%20of%20fish%20oil_SCOPUS.pdf http://irep.iium.edu.my/58010/ http://www.sciencedirect.com/science/article/pii/S1021949817300297
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spelling	my.iium.irep.580102017-08-17T04:16:53Z http://irep.iium.edu.my/58010/ Microencapsulation of fish oil using supercritical antisolvent process Karim, Fahim Tamzeedul Gahfoor, Kashif Ferdosh, Sahena Al-Juhaimi, Fahad Ali, Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam, Ashraful Asif, Mohammad Sarker, Md. Zaidul Islam QD Chemistry In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the optimum response value was evaluated at the conditions of temperature at 60�C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58.35 mm was obtained. The surface morphology of the micronized fish oil was also evaluated using field emission scanning electron microscopy where it showed that particles formed spherical structures with no internal voids. Moreover, in vitro release of oil showed that there are significant differences of release percentage of oil between the formulations and the results proved that there was a significant decrease in the in vitro release of oil from the powder when the polymer concentration was high. Elsevier Taiwan LLC 2017-07 Article REM application/pdf en http://irep.iium.edu.my/58010/1/Microencapsulation%20of%20fish%20oil%20using%20supercritical.pdf application/pdf en http://irep.iium.edu.my/58010/7/58010_Microencapsulation%20of%20fish%20oil_WOS.pdf application/pdf en http://irep.iium.edu.my/58010/8/58010_Microencapsulation%20of%20fish%20oil_SCOPUS.pdf Karim, Fahim Tamzeedul and Gahfoor, Kashif and Ferdosh, Sahena and Al-Juhaimi, Fahad and Ali, Eaqub and Yunus, Kamaruzzaman and Hamed, Mir Hoseini and Islam, Ashraful and Asif, Mohammad and Sarker, Md. Zaidul Islam (2017) Microencapsulation of fish oil using supercritical antisolvent process. Journal of food and drug analysis, 25 (3). 654 -666. ISSN 1021-9498 http://www.sciencedirect.com/science/article/pii/S1021949817300297 10.1016/j.jfda.2016.11.017
institution	Universiti Islam Antarabangsa Malaysia
building	IIUM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	International Islamic University Malaysia
content_source	IIUM Repository (IREP)
url_provider	http://irep.iium.edu.my/
language	English English English
topic	QD Chemistry
spellingShingle	QD Chemistry Karim, Fahim Tamzeedul Gahfoor, Kashif Ferdosh, Sahena Al-Juhaimi, Fahad Ali, Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam, Ashraful Asif, Mohammad Sarker, Md. Zaidul Islam Microencapsulation of fish oil using supercritical antisolvent process
description	In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the optimum response value was evaluated at the conditions of temperature at 60�C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58.35 mm was obtained. The surface morphology of the micronized fish oil was also evaluated using field emission scanning electron microscopy where it showed that particles formed spherical structures with no internal voids. Moreover, in vitro release of oil showed that there are significant differences of release percentage of oil between the formulations and the results proved that there was a significant decrease in the in vitro release of oil from the powder when the polymer concentration was high.
format	Article
author	Karim, Fahim Tamzeedul Gahfoor, Kashif Ferdosh, Sahena Al-Juhaimi, Fahad Ali, Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam, Ashraful Asif, Mohammad Sarker, Md. Zaidul Islam
author_facet	Karim, Fahim Tamzeedul Gahfoor, Kashif Ferdosh, Sahena Al-Juhaimi, Fahad Ali, Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam, Ashraful Asif, Mohammad Sarker, Md. Zaidul Islam
author_sort	Karim, Fahim Tamzeedul
title	Microencapsulation of fish oil using supercritical antisolvent process
title_short	Microencapsulation of fish oil using supercritical antisolvent process
title_full	Microencapsulation of fish oil using supercritical antisolvent process
title_fullStr	Microencapsulation of fish oil using supercritical antisolvent process
title_full_unstemmed	Microencapsulation of fish oil using supercritical antisolvent process
title_sort	microencapsulation of fish oil using supercritical antisolvent process
publisher	Elsevier Taiwan LLC
publishDate	2017
url	http://irep.iium.edu.my/58010/1/Microencapsulation%20of%20fish%20oil%20using%20supercritical.pdf http://irep.iium.edu.my/58010/7/58010_Microencapsulation%20of%20fish%20oil_WOS.pdf http://irep.iium.edu.my/58010/8/58010_Microencapsulation%20of%20fish%20oil_SCOPUS.pdf http://irep.iium.edu.my/58010/ http://www.sciencedirect.com/science/article/pii/S1021949817300297
_version_	1643615263511281664
score	13.211869

Microencapsulation of fish oil using supercritical antisolvent process

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