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Induced mass change technique for glucose detection in microcantilever-based sensors

Microcantilever-based glucose sensor is a state-of-art sensor that has been widely investigated for biosensing applications. This work focuses on the preliminary study of correlation of the glucose reaction and the induced force on the microcantilever sensor by measuring the induced mass changes...

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Main Authors: Mohd Nor, Mardhiah, Bais, Badariah, Abd Aziz, Norazreen, Ab Rahim, Rosminazuin, Yeop Majlis, Burhanuddin
Format: Conference or Workshop Item
Language:English
Published: 2012
Subjects:
T Technology (General)
Online Access:http://irep.iium.edu.my/38797/1/IEEE_Published_ICSE_2012_Mardhiah.pdf
http://irep.iium.edu.my/38797/
http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6417155&tag=1
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spelling my.iium.irep.387972014-10-16T03:05:52Z http://irep.iium.edu.my/38797/ Induced mass change technique for glucose detection in microcantilever-based sensors Mohd Nor, Mardhiah Bais, Badariah Abd Aziz, Norazreen Ab Rahim, Rosminazuin Yeop Majlis, Burhanuddin T Technology (General) Microcantilever-based glucose sensor is a state-of-art sensor that has been widely investigated for biosensing applications. This work focuses on the preliminary study of correlation of the glucose reaction and the induced force on the microcantilever sensor by measuring the induced mass changes due to the glucose reaction. The induced force is then used to test the fabricated microcantilever sensor for glucose detection. Gold-coated glass slides were used as the immobilization sites for glucose oxidase enzyme. The reaction of the glucose oxidase enzyme and ß-D glucose was observed by injecting 5 mM glucose solution on 0.3 mL immobilized enzyme on three samples. The resulted mass changes, ranging from 151.87 mg to 180. 14 mg for the three samples, indicate a good correlation between the enzyme-glucose reaction and the induced mass change. The induced forces of 0.28 μN to 0.29 μN, converted from the mass changes of the glucose-enzyme reaction, is in a range of interactive force values commonly found in biochemical detection applications. 2012 Conference or Workshop Item REM application/pdf en http://irep.iium.edu.my/38797/1/IEEE_Published_ICSE_2012_Mardhiah.pdf Mohd Nor, Mardhiah and Bais, Badariah and Abd Aziz, Norazreen and Ab Rahim, Rosminazuin and Yeop Majlis, Burhanuddin (2012) Induced mass change technique for glucose detection in microcantilever-based sensors. In: 10th IEEE International Conference on Semiconductor Electronics, ICSE 2012, 19-21 September 2012, Kuala Lumpur, Malaysia. http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6417155&tag=1
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic T Technology (General)
spellingShingle T Technology (General)
Mohd Nor, Mardhiah
Bais, Badariah
Abd Aziz, Norazreen
Ab Rahim, Rosminazuin
Yeop Majlis, Burhanuddin
Induced mass change technique for glucose detection in microcantilever-based sensors
description Microcantilever-based glucose sensor is a state-of-art sensor that has been widely investigated for biosensing applications. This work focuses on the preliminary study of correlation of the glucose reaction and the induced force on the microcantilever sensor by measuring the induced mass changes due to the glucose reaction. The induced force is then used to test the fabricated microcantilever sensor for glucose detection. Gold-coated glass slides were used as the immobilization sites for glucose oxidase enzyme. The reaction of the glucose oxidase enzyme and ß-D glucose was observed by injecting 5 mM glucose solution on 0.3 mL immobilized enzyme on three samples. The resulted mass changes, ranging from 151.87 mg to 180. 14 mg for the three samples, indicate a good correlation between the enzyme-glucose reaction and the induced mass change. The induced forces of 0.28 μN to 0.29 μN, converted from the mass changes of the glucose-enzyme reaction, is in a range of interactive force values commonly found in biochemical detection applications.
format Conference or Workshop Item
author Mohd Nor, Mardhiah
Bais, Badariah
Abd Aziz, Norazreen
Ab Rahim, Rosminazuin
Yeop Majlis, Burhanuddin
author_facet Mohd Nor, Mardhiah
Bais, Badariah
Abd Aziz, Norazreen
Ab Rahim, Rosminazuin
Yeop Majlis, Burhanuddin
author_sort Mohd Nor, Mardhiah
title Induced mass change technique for glucose detection in microcantilever-based sensors
title_short Induced mass change technique for glucose detection in microcantilever-based sensors
title_full Induced mass change technique for glucose detection in microcantilever-based sensors
title_fullStr Induced mass change technique for glucose detection in microcantilever-based sensors
title_full_unstemmed Induced mass change technique for glucose detection in microcantilever-based sensors
title_sort induced mass change technique for glucose detection in microcantilever-based sensors
publishDate 2012
url http://irep.iium.edu.my/38797/1/IEEE_Published_ICSE_2012_Mardhiah.pdf
http://irep.iium.edu.my/38797/
http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6417155&tag=1
_version_ 1643611501150339072
score 13.211869

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