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A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus)

A preliminary screening of antifungal activities of skin mucus extract from Malaysian local swamp eel, Monopterus. Albus was performed. The eel’s skin mucus was extracted using two aqueous extraction solvents; distilled water and Phosphate Buffer Sali ne (PBS). In addition, pure mucus was also...

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Main Authors: Mohamed Nor, Nik Mohd Ikram, Hashim, Ridzwan
Format: Article
Language:English
Published: International Research Journals 2013
Subjects:
Q Science (General)
Online Access:http://irep.iium.edu.my/34353/1/a_preliminary_screening_of_antifungal_activities_from_skin_mucus_extract_of_malaysian_local_swamp_eel_monopterus_albus.pdf
http://irep.iium.edu.my/34353/
http://www.interesjournals.org/IRJ PP
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spelling my.iium.irep.343532014-03-24T04:01:37Z http://irep.iium.edu.my/34353/ A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus) Mohamed Nor, Nik Mohd Ikram Hashim, Ridzwan Q Science (General) A preliminary screening of antifungal activities of skin mucus extract from Malaysian local swamp eel, Monopterus. Albus was performed. The eel’s skin mucus was extracted using two aqueous extraction solvents; distilled water and Phosphate Buffer Sali ne (PBS). In addition, pure mucus was also applied without any extraction process. Each extract was pr epared in different concentration via 10-fold seria l dilution and applied onto an agar containing cultur ed fungi using a blank diffusion disc. The method utilized was the disc diffusion sensitivity assay. The tested pathogenic fungi were Candida albicans , Candida krusei , Cryptococcus neoformans and Fusarium spp. PBS extract and pure mucus showed no zone of inhibition for all tested fungi. Water extr act of skin mucus revealed an inhibitory effect on all the fungi whereby Fusarium spp. Was observed to be the most sensitive. The zo ne of inhibition varies from as low as 8 mm to as high as 20 mm but was still de pendent on the incubation period. It was also observed that water acted as a more effective solve nt to extract possible antifungal compound from the skin mucus of M. albus . Throughout, it is suggested that freshwater eel p ossess antifungal activity from its skin mucus and thus supported the claims among locals International Research Journals 2013-01 Article REM application/pdf en http://irep.iium.edu.my/34353/1/a_preliminary_screening_of_antifungal_activities_from_skin_mucus_extract_of_malaysian_local_swamp_eel_monopterus_albus.pdf Mohamed Nor, Nik Mohd Ikram and Hashim, Ridzwan (2013) A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus). International Research Journal of Pharmacy and Pharmacology , 3 (1). pp. 1-8. ISSN 2251-0176 http://www.interesjournals.org/IRJ PP
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic Q Science (General)
spellingShingle Q Science (General)
Mohamed Nor, Nik Mohd Ikram
Hashim, Ridzwan
A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus)
description A preliminary screening of antifungal activities of skin mucus extract from Malaysian local swamp eel, Monopterus. Albus was performed. The eel’s skin mucus was extracted using two aqueous extraction solvents; distilled water and Phosphate Buffer Sali ne (PBS). In addition, pure mucus was also applied without any extraction process. Each extract was pr epared in different concentration via 10-fold seria l dilution and applied onto an agar containing cultur ed fungi using a blank diffusion disc. The method utilized was the disc diffusion sensitivity assay. The tested pathogenic fungi were Candida albicans , Candida krusei , Cryptococcus neoformans and Fusarium spp. PBS extract and pure mucus showed no zone of inhibition for all tested fungi. Water extr act of skin mucus revealed an inhibitory effect on all the fungi whereby Fusarium spp. Was observed to be the most sensitive. The zo ne of inhibition varies from as low as 8 mm to as high as 20 mm but was still de pendent on the incubation period. It was also observed that water acted as a more effective solve nt to extract possible antifungal compound from the skin mucus of M. albus . Throughout, it is suggested that freshwater eel p ossess antifungal activity from its skin mucus and thus supported the claims among locals
format Article
author Mohamed Nor, Nik Mohd Ikram
Hashim, Ridzwan
author_facet Mohamed Nor, Nik Mohd Ikram
Hashim, Ridzwan
author_sort Mohamed Nor, Nik Mohd Ikram
title A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus)
title_short A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus)
title_full A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus)
title_fullStr A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus)
title_full_unstemmed A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus)
title_sort preliminary screening of antifungal activities from skin mucus extract of malaysian local swamp eel (monopterus albus)
publisher International Research Journals
publishDate 2013
url http://irep.iium.edu.my/34353/1/a_preliminary_screening_of_antifungal_activities_from_skin_mucus_extract_of_malaysian_local_swamp_eel_monopterus_albus.pdf
http://irep.iium.edu.my/34353/
http://www.interesjournals.org/IRJ PP
_version_ 1643610610711134208
score 13.211869

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