A preliminary screening of antifungal activities from skin mucus extract of Malaysian local swamp eel (Monopterus albus)
A preliminary screening of antifungal activities of skin mucus extract from Malaysian local swamp eel, Monopterus. Albus was performed. The eel’s skin mucus was extracted using two aqueous extraction solvents; distilled water and Phosphate Buffer Sali ne (PBS). In addition, pure mucus was also...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
International Research Journals
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/34353/1/a_preliminary_screening_of_antifungal_activities_from_skin_mucus_extract_of_malaysian_local_swamp_eel_monopterus_albus.pdf http://irep.iium.edu.my/34353/ http://www.interesjournals.org/IRJ PP |
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| Summary: | A preliminary screening of antifungal activities of
skin mucus extract from Malaysian local swamp eel,
Monopterus. Albus
was performed. The eel’s skin mucus was extracted
using two aqueous extraction
solvents; distilled water and Phosphate Buffer Sali
ne (PBS). In addition, pure mucus was also applied
without any extraction process. Each extract was pr
epared in different concentration via 10-fold seria
l
dilution and applied onto an agar containing cultur
ed fungi using a blank diffusion disc. The method
utilized was the disc diffusion sensitivity assay.
The tested pathogenic fungi were
Candida albicans
,
Candida krusei
,
Cryptococcus neoformans
and
Fusarium
spp. PBS extract and pure mucus showed no
zone of inhibition for all tested fungi. Water extr
act of skin mucus revealed an inhibitory effect on
all the
fungi whereby
Fusarium
spp. Was observed to be the most sensitive. The zo
ne of inhibition varies from
as low as 8 mm to as high as 20 mm but was still de
pendent on the incubation period. It was also
observed that water acted as a more effective solve
nt to extract possible antifungal compound from the
skin mucus of
M. albus
. Throughout, it is suggested that freshwater eel p
ossess antifungal activity from
its skin mucus and thus supported the claims among
locals |
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