Staff View: The impact of intrapartum pethidine on the neonatal outcome. a prospective review

The impact of intrapartum pethidine on the neonatal outcome. a prospective review

Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Methods: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour s...

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Main Authors:	Husin, Roziah, Abdulwahab, Dalia F, Busu Rerah, Ruqaiah, Ismail, Rozihan, Awang, Mokhtar
Format:	Article
Language:	English
Published:	Elsevier Ireland Ltd. 2012
Subjects:	R Medicine (General) RG Gynecology and obstetrics
Online Access:	http://irep.iium.edu.my/29264/1/The_impact_of_intrapartum.pdf http://irep.iium.edu.my/29264/ http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2012.03376.x/abstract
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spelling	my.iium.irep.292642013-03-13T04:00:26Z http://irep.iium.edu.my/29264/ The impact of intrapartum pethidine on the neonatal outcome. a prospective review Husin, Roziah Abdulwahab, Dalia F Busu Rerah, Ruqaiah Ismail, Rozihan Awang, Mokhtar R Medicine (General) RG Gynecology and obstetrics Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Methods: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour suite in Hospital Tengku Ampuan Afzan Kuantan, Malaysia. Intramuscular Pethidine 1 mg/kg was given as intrapartum analgesia to all consented patient with normal baseline fetal heart rate and clear liquor. Intrapartum fetal heart rate pattern and neonatal outcome were reviewed and analysed by SSPS 17.0. Results: Total of 40 patients recruited in this study with mean age of 27.9 ± 6.03 years and mean gestational age of 39.0 ± 0.81 weeks. The mean duration from pethidine administration to delivery is 285.5 ± 178.9 min (4 h and 45 min). Out of 40 patients, two (5%) cases had suspicious CTG 1 h post pethidine administration, first one with absence of acceleration and the second with early deceleration which lasted for 45 min and 1 h respectively. All neonates delivered with good Apgar Score, 8 at 1 min and 9 at 5 min. A total of nine (22.5%) cases were admitted to the Neonatal Intensive Care Unit (NICU). Seven (17.5%) cases were admitted for observation because of delivery <4 h after pethidine administration, following the neonatal protocol at our centre. Two (5%) cases were admitted for G6PD. Neither required ventilation nor antidotes. All of them were discharged to mother after 24 h apart from those admitted because of G6PD. Conclusion: Intrapartum pethidine is still an analgesic option which is simple, cheap and easily available without major effect to the fetal heart rate pattern and the neonatal outcome. Elsevier Ireland Ltd. 2012 Article REM application/pdf en http://irep.iium.edu.my/29264/1/The_impact_of_intrapartum.pdf Husin, Roziah and Abdulwahab, Dalia F and Busu Rerah, Ruqaiah and Ismail, Rozihan and Awang, Mokhtar (2012) The impact of intrapartum pethidine on the neonatal outcome. a prospective review. BJOG: An International Journal of Obstetrics & Gynaecology, 119 (Oct.). p. 83. ISSN ISSN: 1471-0528 (O), 1470-0328 (P) http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2012.03376.x/abstract 10.1111/j.1471-0528.2012.03376.x
institution	Universiti Islam Antarabangsa Malaysia
building	IIUM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	International Islamic University Malaysia
content_source	IIUM Repository (IREP)
url_provider	http://irep.iium.edu.my/
language	English
topic	R Medicine (General) RG Gynecology and obstetrics
spellingShingle	R Medicine (General) RG Gynecology and obstetrics Husin, Roziah Abdulwahab, Dalia F Busu Rerah, Ruqaiah Ismail, Rozihan Awang, Mokhtar The impact of intrapartum pethidine on the neonatal outcome. a prospective review
description	Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Methods: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour suite in Hospital Tengku Ampuan Afzan Kuantan, Malaysia. Intramuscular Pethidine 1 mg/kg was given as intrapartum analgesia to all consented patient with normal baseline fetal heart rate and clear liquor. Intrapartum fetal heart rate pattern and neonatal outcome were reviewed and analysed by SSPS 17.0. Results: Total of 40 patients recruited in this study with mean age of 27.9 ± 6.03 years and mean gestational age of 39.0 ± 0.81 weeks. The mean duration from pethidine administration to delivery is 285.5 ± 178.9 min (4 h and 45 min). Out of 40 patients, two (5%) cases had suspicious CTG 1 h post pethidine administration, first one with absence of acceleration and the second with early deceleration which lasted for 45 min and 1 h respectively. All neonates delivered with good Apgar Score, 8 at 1 min and 9 at 5 min. A total of nine (22.5%) cases were admitted to the Neonatal Intensive Care Unit (NICU). Seven (17.5%) cases were admitted for observation because of delivery <4 h after pethidine administration, following the neonatal protocol at our centre. Two (5%) cases were admitted for G6PD. Neither required ventilation nor antidotes. All of them were discharged to mother after 24 h apart from those admitted because of G6PD. Conclusion: Intrapartum pethidine is still an analgesic option which is simple, cheap and easily available without major effect to the fetal heart rate pattern and the neonatal outcome.
format	Article
author	Husin, Roziah Abdulwahab, Dalia F Busu Rerah, Ruqaiah Ismail, Rozihan Awang, Mokhtar
author_facet	Husin, Roziah Abdulwahab, Dalia F Busu Rerah, Ruqaiah Ismail, Rozihan Awang, Mokhtar
author_sort	Husin, Roziah
title	The impact of intrapartum pethidine on the neonatal outcome. a prospective review
title_short	The impact of intrapartum pethidine on the neonatal outcome. a prospective review
title_full	The impact of intrapartum pethidine on the neonatal outcome. a prospective review
title_fullStr	The impact of intrapartum pethidine on the neonatal outcome. a prospective review
title_full_unstemmed	The impact of intrapartum pethidine on the neonatal outcome. a prospective review
title_sort	impact of intrapartum pethidine on the neonatal outcome. a prospective review
publisher	Elsevier Ireland Ltd.
publishDate	2012
url	http://irep.iium.edu.my/29264/1/The_impact_of_intrapartum.pdf http://irep.iium.edu.my/29264/ http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2012.03376.x/abstract
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score	13.211869

The impact of intrapartum pethidine on the neonatal outcome. a prospective review

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