The impact of intrapartum pethidine on the neonatal outcome. a prospective review
Objective: To study the effect of intrapartum pethidine administration on the fetal heart rate pattern and neonatal outcome. Methods: This is a prospective observational study done on forty low risk uncomplicated pregnancy at term in the first stage of labour. The study was done in the labour s...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier Ireland Ltd.
2012
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/29264/1/The_impact_of_intrapartum.pdf http://irep.iium.edu.my/29264/ http://onlinelibrary.wiley.com/doi/10.1111/j.1471-0528.2012.03376.x/abstract |
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| Summary: | Objective: To study the effect of intrapartum pethidine
administration on the fetal heart rate pattern and neonatal
outcome.
Methods: This is a prospective observational study done on forty
low risk uncomplicated pregnancy at term in the first stage of
labour. The study was done in the labour suite in Hospital
Tengku Ampuan Afzan Kuantan, Malaysia. Intramuscular
Pethidine 1 mg/kg was given as intrapartum analgesia to all
consented patient with normal baseline fetal heart rate and clear
liquor. Intrapartum fetal heart rate pattern and neonatal outcome
were reviewed and analysed by SSPS 17.0.
Results: Total of 40 patients recruited in this study with mean age
of 27.9 ± 6.03 years and mean gestational age of
39.0 ± 0.81 weeks. The mean duration from pethidine
administration to delivery is 285.5 ± 178.9 min (4 h and 45 min).
Out of 40 patients, two (5%) cases had suspicious CTG 1 h post
pethidine administration, first one with absence of acceleration
and the second with early deceleration which lasted for 45 min
and 1 h respectively. All neonates delivered with good Apgar
Score, 8 at 1 min and 9 at 5 min. A total of nine (22.5%) cases
were admitted to the Neonatal Intensive Care Unit (NICU). Seven
(17.5%) cases were admitted for observation because of delivery
<4 h after pethidine administration, following the neonatal
protocol at our centre. Two (5%) cases were admitted for G6PD.
Neither required ventilation nor antidotes. All of them were
discharged to mother after 24 h apart from those admitted
because of G6PD.
Conclusion: Intrapartum pethidine is still an analgesic option
which is simple, cheap and easily available without major effect to
the fetal heart rate pattern and the neonatal outcome. |
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