Unveiling a rarity: myoepithelial neoplasms of soft tissue
Introduction: Myoepithelial neoplasms of soft tissue represent a heterogeneous group of tumours classified as benign (myoepithelioma and mixed tumour) or malignant (myoepithelial carcinoma). Case Presentation: We report the case of a 42-year-old woman with no prior medical conditions who present...
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| Main Authors: | , , , , |
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| Format: | Proceeding Paper |
| Language: | English |
| Published: |
Academy of Medicine Malaysia
2024
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/117421/7/117421_Unveiling%20a%20rarity.pdf http://irep.iium.edu.my/117421/ https://www.mjpath.org.my/ |
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| Summary: | Introduction: Myoepithelial neoplasms of soft tissue represent a heterogeneous group of tumours classified as benign (myoepithelioma
and mixed tumour) or malignant (myoepithelial carcinoma). Case Presentation: We report the case of a 42-year-old woman with
no prior medical conditions who presented with a right arm mass persisting for 15 years. Despite its gradual increase in size, she
remained asymptomatic. Examination revealed a substantial mass in her right arm, with well-defined borders, a soft to firm texture,
and a smooth surface covered by normal skin. MRI of the right humerus showed a lobulated solid-cystic mass, predominantly
cystic, at the postero-medial aspect of the proximal humerus, measuring 7.1 × 7.6 × 11.5 cm. The mass was surgically excised.
Gross examination revealed a well-circumscribed, lobulated-brownish mass measuring 120 × 80 × 60 mm. Cut section showed a
mixture of solid and cystic components, with the solid areas displaying a brownish surface without necrosis. The cystic areas were
multiloculated, ranging from 1-5 mm in diameter, and contained brownish fluid. Microscopic and immunohistochemical analysis
indicated features of a myoepithelial neoplasm of soft tissue. Discussion: Myoepithelial neoplasms of soft tissue exhibit a spectrum
of morphologic patterns, making them difficult to distinguish from other neoplasms. There are no definitive criteria for malignancy
for this tumour. While most morphologically benign myoepithelial neoplasms of soft tissue behave in a benign manner, there is
approximately a 20% risk of local recurrence. Therefore, complete excision with clear margins is crucial. Conclusion: Recognition
of this rare tumour is essential for planning management and predicting prognosis. |
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