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Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study

The objective was to determine the prevalence of positive gel cross match in situation of conjoint negative tube cross match and antibody screening in pre-transfusion testing practices. Study design: Prospective analysis of 2,600 samples with negative gel antibody screening...

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Main Authors: Uday Younis, Hussein, Herda, R. Boher, Afifah, H. Hassan
Format: Article
Published: 2013
Subjects:
Q Science (General)
Online Access:http://eprints.unisza.edu.my/4403/
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spelling my-unisza-ir.44032022-09-13T05:42:09Z http://eprints.unisza.edu.my/4403/ Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study Uday Younis, Hussein Herda, R. Boher Afifah, H. Hassan Q Science (General) The objective was to determine the prevalence of positive gel cross match in situation of conjoint negative tube cross match and antibody screening in pre-transfusion testing practices. Study design: Prospective analysis of 2,600 samples with negative gel antibody screening results was done by tube and gel cross-match techniques in the Transfusion Medicine Unit in National Blood Center / Kuala Lumpur. Results: Positive gel cross-match was detected in 12 out of 2,600 (0.5%) tested samples that have negative both antibody screening and tube cross-match testing results. Six (50%) out of the total positive gel cross-match showed strong agglutination reaction (4+ and 3+ agglutination reaction grade). Conclusion: The situation of reactive gel cross-match with conjoint negative gel antibody screening and conventional tube cross match could occur despite using screening cells that cover most of the clinically significant antigens. 2013-02 Article PeerReviewed Uday Younis, Hussein and Herda, R. Boher and Afifah, H. Hassan (2013) Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study. International journal of medical sciences, 46 (1). pp. 1123-1126. ISSN 2051-5731
institution Universiti Sultan Zainal Abidin
building UNISZA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sultan Zainal Abidin
content_source UNISZA Institutional Repository
url_provider https://eprints.unisza.edu.my/
topic Q Science (General)
spellingShingle Q Science (General)
Uday Younis, Hussein
Herda, R. Boher
Afifah, H. Hassan
Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study
description The objective was to determine the prevalence of positive gel cross match in situation of conjoint negative tube cross match and antibody screening in pre-transfusion testing practices. Study design: Prospective analysis of 2,600 samples with negative gel antibody screening results was done by tube and gel cross-match techniques in the Transfusion Medicine Unit in National Blood Center / Kuala Lumpur. Results: Positive gel cross-match was detected in 12 out of 2,600 (0.5%) tested samples that have negative both antibody screening and tube cross-match testing results. Six (50%) out of the total positive gel cross-match showed strong agglutination reaction (4+ and 3+ agglutination reaction grade). Conclusion: The situation of reactive gel cross-match with conjoint negative gel antibody screening and conventional tube cross match could occur despite using screening cells that cover most of the clinically significant antigens.
format Article
author Uday Younis, Hussein
Herda, R. Boher
Afifah, H. Hassan
author_facet Uday Younis, Hussein
Herda, R. Boher
Afifah, H. Hassan
author_sort Uday Younis, Hussein
title Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study
title_short Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study
title_full Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study
title_fullStr Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study
title_full_unstemmed Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study
title_sort tube versus gel cross match methods at the national blood centre in malaysia: a comparative study
publishDate 2013
url http://eprints.unisza.edu.my/4403/
_version_ 1744358509643825152
score 13.211869

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