Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study
The objective was to determine the prevalence of positive gel cross match in situation of conjoint negative tube cross match and antibody screening in pre-transfusion testing practices. Study design: Prospective analysis of 2,600 samples with negative gel antibody screening...
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| Main Authors: | , , |
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| Format: | Article |
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2013
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| Subjects: | |
| Online Access: | http://eprints.unisza.edu.my/4403/ |
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| Summary: | The objective was to determine the prevalence of positive gel cross match in situation of conjoint negative tube cross match and antibody screening in pre-transfusion testing practices. Study design: Prospective analysis of 2,600 samples with negative gel antibody screening results was done by tube and gel cross-match techniques in the Transfusion Medicine Unit in National Blood Center / Kuala Lumpur. Results: Positive gel cross-match was detected in 12 out of 2,600 (0.5%) tested samples that have negative both antibody screening and tube cross-match testing results. Six (50%) out of the total positive gel cross-match showed strong agglutination reaction (4+ and 3+ agglutination reaction grade). Conclusion: The situation of reactive gel cross-match with conjoint negative gel antibody screening and conventional tube cross match could occur despite using screening cells that cover most of the clinically significant antigens. |
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