Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopat...
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Faculty of Medicine, UKM Medical Centre
2016
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Online Access: | http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf http://journalarticle.ukm.my/9841/ http://jsurgacad.com/toc/6/1 |
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my-ukm.journal.98412016-12-14T06:51:00Z http://journalarticle.ukm.my/9841/ Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery. Faculty of Medicine, UKM Medical Centre 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf Lee, CL and Aini Amelia Zainuddin, and Abdul Kadir Abdul Karim, and Yulianty Arifuddin, and Law, Zhee Kang and Md. Isa N, and Nor Azlin Mohamed Ismail, (2016) Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis. Journal of Surgical Academia, 6 (1). pp. 66-69. ISSN 2231-7481 http://jsurgacad.com/toc/6/1 |
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We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery. |
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Article |
author |
Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, |
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Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
author_facet |
Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, |
author_sort |
Lee, CL |
title |
Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
title_short |
Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
title_full |
Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
title_fullStr |
Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
title_full_unstemmed |
Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
title_sort |
anti n-methyl-d-aspartate receptor encephalitis with ovarian teratoma: a dilemma in diagnosis |
publisher |
Faculty of Medicine, UKM Medical Centre |
publishDate |
2016 |
url |
http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf http://journalarticle.ukm.my/9841/ http://jsurgacad.com/toc/6/1 |
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1643737922142208000 |
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13.211869 |