Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis

We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopat...

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Main Authors: Lee, CL, Aini Amelia Zainuddin,, Abdul Kadir Abdul Karim,, Yulianty Arifuddin,, Law, Zhee Kang, Md. Isa N,, Nor Azlin Mohamed Ismail,
Format: Article
Language:English
Published: Faculty of Medicine, UKM Medical Centre 2016
Online Access:http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf
http://journalarticle.ukm.my/9841/
http://jsurgacad.com/toc/6/1
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spelling my-ukm.journal.98412016-12-14T06:51:00Z http://journalarticle.ukm.my/9841/ Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis Lee, CL Aini Amelia Zainuddin, Abdul Kadir Abdul Karim, Yulianty Arifuddin, Law, Zhee Kang Md. Isa N, Nor Azlin Mohamed Ismail, We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery. Faculty of Medicine, UKM Medical Centre 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf Lee, CL and Aini Amelia Zainuddin, and Abdul Kadir Abdul Karim, and Yulianty Arifuddin, and Law, Zhee Kang and Md. Isa N, and Nor Azlin Mohamed Ismail, (2016) Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis. Journal of Surgical Academia, 6 (1). pp. 66-69. ISSN 2231-7481 http://jsurgacad.com/toc/6/1
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery.
format Article
author Lee, CL
Aini Amelia Zainuddin,
Abdul Kadir Abdul Karim,
Yulianty Arifuddin,
Law, Zhee Kang
Md. Isa N,
Nor Azlin Mohamed Ismail,
spellingShingle Lee, CL
Aini Amelia Zainuddin,
Abdul Kadir Abdul Karim,
Yulianty Arifuddin,
Law, Zhee Kang
Md. Isa N,
Nor Azlin Mohamed Ismail,
Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
author_facet Lee, CL
Aini Amelia Zainuddin,
Abdul Kadir Abdul Karim,
Yulianty Arifuddin,
Law, Zhee Kang
Md. Isa N,
Nor Azlin Mohamed Ismail,
author_sort Lee, CL
title Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_short Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_full Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_fullStr Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_full_unstemmed Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
title_sort anti n-methyl-d-aspartate receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
publisher Faculty of Medicine, UKM Medical Centre
publishDate 2016
url http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf
http://journalarticle.ukm.my/9841/
http://jsurgacad.com/toc/6/1
_version_ 1643737922142208000
score 13.211869