Cover Image

Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain

The levels of malondialdehyde (MDA)-specific antibodies in lupus-prone MRL/ lpr mice of different ages were compared to those against DNA. These mice elicited anti-MDA antibodies earlier and in higher levels that anti-DNA antibodies. The levels of immune complexes containing MDA adducts were also hi...

Full description

Saved in:
Bibliographic Details
Main Authors: Danial Yahya, M., Chien , C. Lung, Yacob L. Pinnas,
Format: Article
Published: Universiti Kebangsaan Malaysia 1996
Online Access:http://journalarticle.ukm.my/3681/
http://www.ukm.my/jsm/english_journals/vol25num1_1996/vol25num1_96page77-86.html
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-ukm.journal.3681
record_format eprints
spelling my-ukm.journal.36812012-03-29T04:33:57Z http://journalarticle.ukm.my/3681/ Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain Danial Yahya, M. Chien , C. Lung Yacob L. Pinnas, The levels of malondialdehyde (MDA)-specific antibodies in lupus-prone MRL/ lpr mice of different ages were compared to those against DNA. These mice elicited anti-MDA antibodies earlier and in higher levels that anti-DNA antibodies. The levels of immune complexes containing MDA adducts were also higher in these mice when compared to 3 other non-lupus strains. MDA binding to a 100 kDa serum protein was observed in 3 and 5 month old mice. Immune complexes involving anti-MDA antibodies and MDA adducts may represent an additional mechanism that contributes to disease pathogenesis in these mice. Universiti Kebangsaan Malaysia 1996-03 Article PeerReviewed Danial Yahya, M. and Chien , C. Lung and Yacob L. Pinnas, (1996) Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain. Sains Malaysiana, 25 (1). pp. 77-86. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol25num1_1996/vol25num1_96page77-86.html
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
description The levels of malondialdehyde (MDA)-specific antibodies in lupus-prone MRL/ lpr mice of different ages were compared to those against DNA. These mice elicited anti-MDA antibodies earlier and in higher levels that anti-DNA antibodies. The levels of immune complexes containing MDA adducts were also higher in these mice when compared to 3 other non-lupus strains. MDA binding to a 100 kDa serum protein was observed in 3 and 5 month old mice. Immune complexes involving anti-MDA antibodies and MDA adducts may represent an additional mechanism that contributes to disease pathogenesis in these mice.
format Article
author Danial Yahya, M.
Chien , C. Lung
Yacob L. Pinnas,
spellingShingle Danial Yahya, M.
Chien , C. Lung
Yacob L. Pinnas,
Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain
author_facet Danial Yahya, M.
Chien , C. Lung
Yacob L. Pinnas,
author_sort Danial Yahya, M.
title Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain
title_short Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain
title_full Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain
title_fullStr Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain
title_full_unstemmed Levels of malondialdehyde-related immune reactants in a lupus prone mouse strain
title_sort levels of malondialdehyde-related immune reactants in a lupus prone mouse strain
publisher Universiti Kebangsaan Malaysia
publishDate 1996
url http://journalarticle.ukm.my/3681/
http://www.ukm.my/jsm/english_journals/vol25num1_1996/vol25num1_96page77-86.html
_version_ 1643735809534197760
score 13.211869

Similar Items