Cover Image

Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches

The mathematical modelling provides an alternative way for the interpretation and prediction of cellular metabolisms. This study delves into the modelling of lipid biosynthesis pathway and the primary metabolism in the fruit of the oil palm (Elaeis guineensis). Two different data are used for th...

Full description

Saved in:
Bibliographic Details
Main Authors: Quek, Emily Ming Poh, Purutcuoglu, Vilda, Sambanthamurthi, Ravigadevi, WilhelmWeber, Gerhard
Format: Book Section
Language:English
Published: IEEE 2011
Subjects:
TP Chemical technology
Online Access:http://eprints.intimal.edu.my/190/1/12.pdf
http://eprints.intimal.edu.my/190/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-inti-eprints.190
record_format eprints
spelling my-inti-eprints.1902016-04-20T08:42:48Z http://eprints.intimal.edu.my/190/ Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches Quek, Emily Ming Poh Purutcuoglu, Vilda Sambanthamurthi, Ravigadevi WilhelmWeber, Gerhard TP Chemical technology The mathematical modelling provides an alternative way for the interpretation and prediction of cellular metabolisms. This study delves into the modelling of lipid biosynthesis pathway and the primary metabolism in the fruit of the oil palm (Elaeis guineensis). Two different data are used for the analysis. In the first dataset, the distribution of carbon flux into the major classes of lipids, i.e., triacylglycerols, diacylglycerols, monoacylglycerols, phospholipids, and free fatty acids, is investigated using radioactive isotope. Then, the model of carbon flux is constructed based on the Boolean approach. On the other hand in the second dataset, the graphical methods are implemented to construct a model for the lipid contents of the developing oil palm mesocarp based on the major lipid metabolites of this system as listed previously. Moreover, the generated models are analysed for the control structure depending on the relative ranking of degree for each lipid class in the pathway. The results demonstrate the ability of the models to predict the site of control in this biosynthetic system. Furthermore, the analyses of the networks of lipids do not only reveal underlying interactions between the major classes of lipids but also the response of these networks towards changing environments. IEEE 2011 Book Section PeerReviewed text en http://eprints.intimal.edu.my/190/1/12.pdf Quek, Emily Ming Poh and Purutcuoglu, Vilda and Sambanthamurthi, Ravigadevi and WilhelmWeber, Gerhard (2011) Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches. In: 2011 6th International Health Informatics and Bioinformatics (HIBIT). IEEE, pp. 129-135. ISBN 978-2-4673-4394-4 10.1109/HIBIT.2011.6450822
institution INTI International University
building INTI Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider INTI International University
content_source INTI Institutional Repository
url_provider http://eprints.intimal.edu.my
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Quek, Emily Ming Poh
Purutcuoglu, Vilda
Sambanthamurthi, Ravigadevi
WilhelmWeber, Gerhard
Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches
description The mathematical modelling provides an alternative way for the interpretation and prediction of cellular metabolisms. This study delves into the modelling of lipid biosynthesis pathway and the primary metabolism in the fruit of the oil palm (Elaeis guineensis). Two different data are used for the analysis. In the first dataset, the distribution of carbon flux into the major classes of lipids, i.e., triacylglycerols, diacylglycerols, monoacylglycerols, phospholipids, and free fatty acids, is investigated using radioactive isotope. Then, the model of carbon flux is constructed based on the Boolean approach. On the other hand in the second dataset, the graphical methods are implemented to construct a model for the lipid contents of the developing oil palm mesocarp based on the major lipid metabolites of this system as listed previously. Moreover, the generated models are analysed for the control structure depending on the relative ranking of degree for each lipid class in the pathway. The results demonstrate the ability of the models to predict the site of control in this biosynthetic system. Furthermore, the analyses of the networks of lipids do not only reveal underlying interactions between the major classes of lipids but also the response of these networks towards changing environments.
format Book Section
author Quek, Emily Ming Poh
Purutcuoglu, Vilda
Sambanthamurthi, Ravigadevi
WilhelmWeber, Gerhard
author_facet Quek, Emily Ming Poh
Purutcuoglu, Vilda
Sambanthamurthi, Ravigadevi
WilhelmWeber, Gerhard
author_sort Quek, Emily Ming Poh
title Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches
title_short Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches
title_full Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches
title_fullStr Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches
title_full_unstemmed Modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches
title_sort modelling lipid biosynthesis pathways of oil palm by boolean and graphical approaches
publisher IEEE
publishDate 2011
url http://eprints.intimal.edu.my/190/1/12.pdf
http://eprints.intimal.edu.my/190/
_version_ 1644541143131619328
score 13.211869

Similar Items