Inhibition of NEDD8 and FAT10 ligase activities through the degrading enzyme NEDD8 ultimate buster 1: A potential anticancer approach (review)

The capabilities of tumour cells to survive through deregulated cell cycles and evade apoptosis are hallmarks of cancer. The ubiquitin-like proteins (UBL) proteasome system is important in regulating cell cycles via signaling proteins. Deregulation of the proteasomal system can lead to uncontrolled...

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Bibliographic Details

Main Authors:	Tan K.-L., Pezzella F.
Other Authors:	Faculty of Medicine and Health Sciences
Format:	Article
Language:	English en_US
Published:	Spandidos Publications 2024
Subjects:	Cullins E3 ubiquitin ligases FAT10 NEDD8 NUB1 Proteasomal degradation Ubiquitin-like proteins
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