Synthesis, Antibacterial Activity And Cytotoxicity Of New Fused Pyrazolo[1,5-a]pyrimidine And Pyrazolo[5,1-c][1,2,4]triazine Derivatives From New 5-aminopyrazoles

New 5-aminopyrazoles2aec were prepared in high yields from the reaction of knowna,a-dicyanoke-tene-N,S-acetals1aec with hydrazine hydrate under reflux in ethanol. These compounds were utilized as intermediates to synthesize pyrazolo[1,5-a]-pyrimidines3aec,4aed,5aec, and6aec, as well as pyrazolo[5,1-...

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Bibliographic Details

Main Authors:	Siti Noor Adnalizawati Adnan, Wedad M. Al-Adiwish, M.I.M. Tahir, Siti Farah Hashim, Nazlina Ibrahim, W.A. Yaacob
Format:	Article
Language:	en_US
Published:	Elsevier 2024
Subjects:	5-Aminopyrazoles,Pyrazolo[1,5-a]pyrimidines,Pyrazolo[5,1-c][1,2,4]triazinesa, a-Dicyanoketene-S,S- and N,S-acetals,Antibacterial activity,Cytotoxicity
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