Immunization With Recombinant Chaperonin60 (chp60) Outer Membrane Protein Induces A Bactericidal Antibody Response Against Neisseria Meningitidis

Sera from individuals colonized with Neisseria meningitidis and from patients with meningococcal disease contain antibodies specific for the neisserial heat-shock/chaperonin (Chp)60 protein. In this study, immunization of mice with recombinant (r)Chp60 in saline; adsorbed to aluminium hydroxide; in...

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Bibliographic Details

Main Authors:	Renee Phillips, Jeannette N Williams, Wei-Ming Tan, Magdalena K Bielecka, Hannah Thompson, Miao-Chiu Hung, John E Heckels, Myron Christodoulides
Format:	Article
Language:	en
Published:	Elsevier 2024
Subjects:	Chaperonin60 Neisseria meningitidis Bactericidal Antibody Vaccine
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