Enzymatic synthesis of betulinic acid ester as an anticancer agent: optimization study
Immobilized Candida antarctica lipase, Novozym 435, was used to catalyze the esterification reaction between betulinic acid and phthalic anhydride to synthesize 3-O-phthalyl betulinic acid in n-hexane/chloroform. Response surface methodology based on a five-level, four-variable central composite rot...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | en |
| Published: |
Informa Healthcare
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/14540/1/Enzymatic%20synthesis%20of%20betulinic%20acid%20ester%20as%20an%20anticancer%20agent.pdf http://psasir.upm.edu.my/id/eprint/14540/ http://www.tandfonline.com/doi/abs/10.3109/10242421003753795?journalCode=ibab20 |
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