Oxymatrine attenuates melanoma progression and metastasis through SORBS2-mediated suppression of M2 macrophage polarization

Background Melanoma is an aggressive malignancy characterized by a highly immunosuppressive tumor microenvironment (TME), in which tumor-associated macrophages (TAMs) play a key role. Although oxymatrine (OMT) has been shown to exert anticancer effects, its mechanism of action in melanoma, particula...

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Main Authors:	Li, Xin, Ou, Yanhua, Chen, Jinling, Xiong, Junlong, Xu, Fangwen, Hu, Yaqian, Chen, Yuhan, Bai, Kunran, Chen, Jingyi, Meng, Yong, He, Jun, Lai, Caiyong, Niu, Haitao
Format:	Article
Language:	en
Published:	Elsevier GmbH 2026
Subjects:	Molecular Medicine Pharmacology Pharmaceutical Science
Online Access:	http://psasir.upm.edu.my/id/eprint/124712/1/124712.htm http://psasir.upm.edu.my/id/eprint/124712/ https://linkinghub.elsevier.com/retrieve/pii/S094471132600382X
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