Translocating shRNA: a novel approach to RNA interference with Newcastle disease virus as viral vector

RNA interference is crucial in post-transcriptional gene silencing. Short hairpin RNA (shRNA) is particularly effective because it forms fully complementary matches with target mRNA, leading to its degradation. However, shRNA processing relies on nuclear microprocessors like Drosha, posing a challen...

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Bibliographic Details
Main Authors: Koh, Wei Chin, Yusoff, Khatijah, Song, Adelene Ai Lian, Saad, Norazalina, Tan, Tiong Kit, Cheow, Pheik Sheen, Chia, Suet Lin
Format: Article
Language:en
Published: Microbiology Society 2025
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Online Access:http://psasir.upm.edu.my/id/eprint/124406/1/124406.pdf
http://psasir.upm.edu.my/id/eprint/124406/
https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.002127
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