Comparative effectiveness of immediate-release and extended-release metformin on gastrointestinal tolerability, quality of life, and treatment satisfaction: a prospective cohort study

Gastrointestinal (GI) side effects from metformin often limit its use and can impact patient quality of life (QoL) and satisfaction. The extended-release (XR) formulation is thought to cause fewer GI adverse events than immediate-release (IR) metformin, potentially improving tolerability, treatment...

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Bibliographic Details
Main Authors: Alshadfan, Hisham, Mirghani, Hyder, Alrasheed, Tariq, Alanazi, Mansuor, Alatawi, Amirah, Elodemi, Mahmoud, Abdullah, Muhammad Nazrul Hakim
Format: Article
Language:en
Published: Wolters Kluwer Health 2026
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/123416/1/123416.pdf
http://psasir.upm.edu.my/id/eprint/123416/
https://journals.lww.com/10.1097/MD.0000000000046320
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