Neuroprotective mechanisms of Ficus deltoidea in an Alzheimer’s disease-like rat model: targeting tau hyperphosphorylation through glycogen synthase kinase-3 beta and protein phosphatase 2a regulation

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterised by memory loss, neurodegeneration, amyloid plaque accumulation and tau hyperphosphorylation. Dysregulation of glycogen synthase kinase-3β (GSK-3β) and protein phosphatase 2 A (PP2A) plays a pivotal role in tau patholo...

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Main Authors:	Manoharan, Sushmitaa Dhevii, Usman, Abdulhamid Sani, Abdul Hamid, Hafizah, Che Mohd Nassir, Che Mohd Nasril, Cheema, Manraj Singh, Che Ramli, Muhammad Danial, Mohd Moklas, Mohamad Aris, Mehat, Muhammad Zulfadli
Format:	Article
Language:	en
Published:	Springer 2026
Subjects:	Biochemistry Cellular and Molecular Neuroscience
Online Access:	http://psasir.upm.edu.my/id/eprint/123304/1/123304.pdf http://psasir.upm.edu.my/id/eprint/123304/ https://link.springer.com/article/10.1007/s11064-026-04702-0
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