Synthesis of CNP-SAR405 delivery system for improved therapeutics anticancer activity using A549 human lung cancer cell lines

Autophagy, a critical homeostatic process, is increasingly implicated in cancer progression and therapy resistance. SAR405 is a potent inhibitor of the autophagy related PIK3C3/VPS34 complex, offering potential as an anticancer agent. This study reports the synthesis, characterization, and biologica...

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Bibliographic Details
Main Authors: Bashirah, Ruqayyah A., Zamri, Nur Balqis, Alitheen, Noorjahan Banu, Ismail, Saila, Masarudin, Mas Jaffri
Format: Article
Language:en
Published: Springer Science and Business Media Deutschland GmbH 2025
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Online Access:http://psasir.upm.edu.my/id/eprint/123284/1/123284.pdf
http://psasir.upm.edu.my/id/eprint/123284/
https://link.springer.com/article/10.1007/s00210-025-04592-z
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