Chlorogenic acid-rich Morus alba leaf alleviated renal fibrosis through the regulation of transforming growth factor-beta 1 (TGF-β1) and fibroblast growth factor-2 (FGF-2), and extracellular matrix deposition

Background: Chronic kidney disease (CKD) progression is linked to renal fibrosis, influenced by profibrotic factors like transforming growth factor-beta 1 (TGF-β1) and fibroblast growth factor-2 (FGF-2). Despite advancements in synthetic drugs like enalapril, evidence for plant-derived candidates th...

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Main Authors: Fauzi, Ahmad, Atho’illah, Mochammad Fitri, Titisari, Nurina, Noor, Mohd Hezmee Mohd, Azlan, Azrina, Hamzah, Hazilawati
Format: Article
Language:en
Published: Springer Science and Business Media 2025
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/121995/1/121995.pdf
http://psasir.upm.edu.my/id/eprint/121995/
https://link.springer.com/article/10.1007/s11033-025-11209-4
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