Prenatal ruxolitinib treatment improved muscle strength but showed no impact on the neurobehavioral and electrophysiological traits in adult mice
The JAK/STAT signalling pathway is essential for cell communication and gene expression, particularly in brain development. Its dysregulation relates to neurological conditions such as Down syndrome and Noonan syndrome, impacting the shift from neuron to astrocyte production. Ruxolitinib, an FDA app...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | en |
| Published: |
Pleiades Publishing
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/119356/1/119356.pdf http://psasir.upm.edu.my/id/eprint/119356/ https://link.springer.com/article/10.1134/S1819712424700168?error=cookies_not_supported&code=e0e8224d-c9b7-4237-a1a3-7e8b1c3d54d4 |
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