Reduced REST expression in neural progenitor cells, adult cortex, and impaired REST nuclear translocation in the prefrontal cortex of Ts1Cje mouse model of Down Syndrome
Abstract—Down syndrome (DS) is a common genetic disorder caused by trisomy of human chromosome 21. DS individuals have neurodevelopmental defects that lead to the manifestation of neurological and neuropsychiatric disorders. Repressor element-1 silencing transcription factor (REST) is the key epigen...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | en |
| Published: |
Pleiades Publishing
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/117088/1/117088.pdf http://psasir.upm.edu.my/id/eprint/117088/ https://link.springer.com/article/10.1134/S1819712424010148?error=cookies_not_supported&code=0e04fc1c-5994-485c-ac4b-516a73f9f5a7 |
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