Lithium restores nuclear REST and Mitigates oxidative stress in down syndrome iPSC-Derived neurons
Down syndrome (DS), caused by trisomy 21, is characterized by intellectual disability and accelerated aging, with chronic oxidative stress contributing to neurological deficits. REST (Repressor Element-1 Silencing Transcription factor) is a crucial regulator of neuronal gene expression implicated in...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | en en |
| Published: |
Elsevier Science
2025
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/115894/1/115894.pdf http://psasir.upm.edu.my/id/eprint/115894/2/115894-published.pdf http://psasir.upm.edu.my/id/eprint/115894/ https://linkinghub.elsevier.com/retrieve/pii/S0306-4522(24)00774-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|