Chromosomal and cellular therapeutic approaches for Down syndrome: a research update
In individuals with Down syndrome (DS), an additional HSA21 chromosome copy leads to the overexpression of a myriad of HSA21 genes, disrupting the transcription of the entire genome. This dysregulation in transcription and post-transcriptional modifications contributes to abnormal phenotypes across...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | en |
| Published: |
Elsevier
2024
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/115209/1/115209.pdf http://psasir.upm.edu.my/id/eprint/115209/ https://www.sciencedirect.com/science/article/pii/S0006291X24012002?via%3Dihub |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|