Amphotericin B resistance in Leishmania mexicana: alterations to sterol metabolism and oxidative stress response

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed that, in each resistant...

Full description

Bibliographic Details

Main Authors:	Alpizar-Sosa, Edubiel A., Ithnin, Nur Raihana, Wenbin, Wei, Pountain, Andrew W., Weidt, Stefan K., Donachie, Anne M., Ritchie, Ryan, Dickie, Emily A., Burchmore, Richard J. S., Denny, Paul W., Barrett, Michael P.
Format:	Article
Published:	Public Library of Science 2022
Online Access:	http://psasir.upm.edu.my/id/eprint/100188/ https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0010779
Tags:	Add Tag No Tags, Be the first to tag this record!