Dimerization of SARS-CoV-2 3CLpro and the Role of the A7G/V125G Zipper Interface

Introduction/Objectives: The 3-chymotrypsin-like protease (3CLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for viral replication and is catalytically active only in its dimeric form. Elucidating the molecular determinants that stabilize this dimer may uncover no...

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Bibliographic Details
Main Authors: Rafida, Razali, Cahyo, Budiman, Vijay, Kumar
Format: Article
Language:en
Published: Bentham Science Publishers 2026
Subjects:
Online Access:http://ir.unimas.my/id/eprint/51874/2/Dimerization.pdf
http://ir.unimas.my/id/eprint/51874/
https://www.benthamscience.com/article/154159
https://doi.org/10.2174/0109298665442327260216063524
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