A New Class of Vitamin K Analogues Containing the Side Chain of Retinoic Acid Have Enhanced Activity for Inducing Neuronal Differentiation

Vitamin K, primarily known for its roles in coagulation and bone metabolism, has recently been implicated in neuroprotection and neuronal differentiation, particularly via its bioactive form, menaquinone-4 (MK-4). Here, we synthesized 12 vitamin K compounds with retinoic acidconjugated side chains...

Full description

Bibliographic Details

Main Authors:	Yoshihisa, Hirota, Taiki, Sato, Rina, Watanabe, Kazuki, Takeda, Sho, Sano, Satoshi, Asano, Yuki, Shibahashi, Yumi, Yusada, Yuta, Takagi, Yutaro, Yamashita, Wu, YuXin, Mikino, Arakawa, Yuri, Maitani, Vannessa, Lawai, Kurumi, Nakagawa, Natsuko, Furukawa, Atsuko, Takeuchi, Chisato, Tode, Maya, Kamao, Akimori, Wada, Zainab, Ngaini
Format:	Article
Language:	en
Published:	American Chemical Society 2025
Subjects:	QD Chemistry
Online Access:	http://ir.unimas.my/id/eprint/49022/1/A%20New%20Class%20of%20Vitamin%20K.pdf http://ir.unimas.my/id/eprint/49022/ https://pubs.acs.org/doi/full/10.1021/acschemneuro.5c00111 https://doi.org/10.1021/acschemneuro.5c00111
Tags:	Add Tag No Tags, Be the first to tag this record!