An 8-year-old girl with secondary histiocytic sarcoma with BRAFV600 mutation following T-cell acute lymphoblastic leukemia demonstrating stable disease for 3 years on dabrafenib and trametinib – a case report and literature review

Abstract Background Histiocytic sarcoma as a secondary malignancy following childhood leukemia is extremely uncommon with fewer than 20 cases reported worldwide. They often pose a diagnostic challenge and prognosis is dismal. There is a lack of well-established clinical treatment protocols owing...

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Bibliographic Details
Main Authors: Tan, Sue Lyn, Betty Ho, Lee Sue, Yew, Ting Ting, Dahziela, Yunus
Format: Article
Language:en
Published: BioMed Central Ltd. 2025
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Online Access:http://ir.unimas.my/id/eprint/47723/1/BMC%20Histiocytic%20sarcoma.pdf
http://ir.unimas.my/id/eprint/47723/
https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-025-05539-2
https://doi.org/10.1186/s12887-025-05539-2
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