Effect of reaction parameters on the lipase-catalyzed kinetic resolution of (RS)-metoprolol

Racemic metoprolol is a selective �1-blocker, which is used in cardiovascular disease treatment. It has been found that (S)-metoprolol has a higher affinity to bind the �-adrenergic receptor compared to (R)-metoprolol. Moreover, the regulatory authorities� high market demand and guidelines have...

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Bibliographic Details

Main Authors:	Mariani, Rajin, Asiah, Zulkifli, Sariah, Abang, S. M., Anissuzzaman, A. H., Kamaruddin
Format:	Article
Language:	en
Published:	ASEAN Chemical Engineers 2020
Subjects:	T Technology (General) TP Chemical technology
Online Access:	http://ir.unimas.my/id/eprint/42946/3/Effect%20of%20Reaction.pdf http://ir.unimas.my/id/eprint/42946/ https://jurnal.ugm.ac.id/AJChE/article/view/51857 https://doi.org/10.22146/ajche.51857
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