An injectable composite hydrogel enhances bone regeneration by rescuing impaired mitochondrial biogenesis and fusion of BMSCs under inflammatory conditions

The treatment of severe bone defects remains an unresolved clinical challenge. Injectable hydrogels loaded with drugs or growth factors are considered to offer substantial benefits in the regeneration of bone defects with irregular shapes under complex pathological microenvironments. In this study,...

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Main Authors: Weizhou Jiang, Zhijie Pan, Zongze Zhang, Xingchen Yan, Praneetha Palasuberniam, Jun Xiao, Jianlin Shen, Donghong Guo, Yang Zhang, Huan Liu
Format: Article
Language:en
Published: ACS Publications 2025
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Online Access:https://eprints.ums.edu.my/id/eprint/44920/1/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/44920/
https://doi.org/10.1021/acsapm.4c03332
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