Dacarbazine induces genotoxic and cytotoxic germ cell damage with concomitant decrease in testosterone and increase in lactate dehydrogenase concentration in the testis
Treatment of cancers with cytotoxic agents such as alkylating drugs often, but not always results in transient to permanent testicular dysfunction. The present study was planned to investigate the effects of dacarbazine [5-(3,3-dimethyltriazeno) imidazole-4-carboxamide] on testicular function in mic...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Elsevier
2006
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| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/1131/ http://dx.doi.org/10.1016/j.mrgentox.2006.04.019 |
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