Repurposing sulfonamide-based antidiabetic agents against polycystic ovary syndrome: a molecular docking and dynamics simulation approach

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive age, marked by hyperinsulinemia, hyperandrogenism, menstrual irregularities, and long-term metabolic complications. Cytochrome P450 17A1 (CYP17A1) is a key enzyme in the biosynthesis of adrenal and gon...

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Bibliographic Details

Main Authors:	Roney, Miah, Issahaku, Abdul Rashid, Hamim, S.M. Istiaque, Wilhelm, Anke, Mohd Fadhlizil Fasihi, Mohd Aluwi
Format:	Article
Language:	en
Published:	Springer 2025
Subjects:	RM Therapeutics. Pharmacology RS Pharmacy and materia medica
Online Access:	https://umpir.ump.edu.my/id/eprint/47253/1/Repurposing%20sulfonamide-based%20antidiabetic%20agents%20against%20polycystic%20ovary.pdf https://doi.org/10.1007/s12247-025-10119-z https://umpir.ump.edu.my/id/eprint/47253/
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