In vitro and in vivo anti-inflammatory activities of columbin through the inhibition of cycloxygenase-2 and nitric oxide but not the suppression of NF-κB translocation

Columbin, a diterpenoid furanolactone, was isolated purely for the first time from the plant species Tinspora bakis. The anti-inflammatory effects of columbin were studied in vitro, in silico and in vivo. The effect of columbin on nitric oxide was examined on lipopolysaccharide–interferon-gamma (LPS...

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Main Authors:	Abdelwahab, S. I., Koko, W. S., Taha, M. M. E., Mohan, S., Achoui, M., Abdulla, M. A., Mustafa, Mohd Rais, Ahmad, S., Noordin, M. I., Yong, C. L.
Format:	Article
Language:	en
Published:	Elsevier 2011
Subjects:	QD Chemistry RM Therapeutics. Pharmacology
Online Access:	http://eprints.um.edu.my/3021/1/In_vitro_and_in_vivo_anti-inflammatory_activities_of_columbin_through_the_inhibition_of.pdf http://eprints.um.edu.my/3021/ http://www.sciencedirect.com/science/article/pii/S0014299911015585
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