The mechanism of formation, structure and physiological relevance of covalent hemoglobin attachment to the erythrocyte membrane
Covalent hemoglobin binding to membranes leads to band 3 (AE1) clustering and the removal of erythrocytes from the circulation; it is also implicated in blood storage lesions. Damaged hemoglobin, with the heme being in a redox and oxygen-binding inactive hemichrome form, has been implicated as the b...
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| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Elsevier
2017
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/22811/ https://doi.org/10.1016/j.freeradbiomed.2016.12.024 |
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