p53: an overview of over two decades of study
p53 is the most commonly mutated gene in human cancers. It encodes a 53 kilodalton protein with several evolutionarily conserved domains viz sequence-specific DNA binding, tetramerisation, SH3 molecule binding, C-terminal and N-terminal. Existing in the cell at a very low level and in a relatively i...
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| Format: | Article |
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College of Pathologists, Academy of Medicine Malaysia
2001
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| Online Access: | http://eprints.um.edu.my/1612/ http://www.mjpath.org.my/past_issue/MJP2001.1/P53.pdf |
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