Molecular Dynamics and Docking of Biphenyl: A Potential Attachment Inhibitor for HIV-1 gp120 Glycoprotein

Purpose: To develop a new drug that inhibits viral attachment and entry for the treatment of HIV/AIDS patients. Methods: Two Protein Databank (PDB) crystal structures of HIV-1 gp120-CD4 complexes, namely, 1RZK and 1G9N, were mutated at amino acid position 43 to a biphenylalanine (biPhe-43) residu...

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Bibliographic Details

Main Authors:	Teow, C.T., Ismail, Salmah, Jung, M.T.
Format:	Article
Published:	Pharmacotherapy Group, University of Benin, Benin City 2014
Subjects:	Q Science (General) QH Natural history
Online Access:	http://eprints.um.edu.my/14523/ http://www.tjpr.org/vol13_no3/2014_13_3_4.php http://dx.doi.org/10.4314/tjpr.v13i3.4
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